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Graphical presentation of CX-5461-mediated activation of the cytosolic DNA sensing pathway. cGAS binding to the cytosolic DNA activates the secondary messenger 2,3-cGAMP working with cGAS to be a catalyst. Activated STING buds off the ER transferring on the perinuclear Golgi, wherever it truly is palmitoylated.To avoid the motion of huge enemy grou
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